Post-Exertional Malaise May Be Related to Central Blood Pressure, Sympathetic Activity and Mental Fatigue in Chronic Fatigue Syndrome Patients

Post-exertional malaise (PEM) is regarded as the hallmark symptom in chronic fatigue syndrome (CFS). The aim of current study to explore differences CFS patients with and without PEM indicators aortic stiffness, autonomic nervous system function, severity fatigue. One-hundred one met Fukuda criteria. A Chronic Fatigue Questionnaire (CFQ) Impact Scale (FIS) were used assess level mental physical Aortic systolic blood pressure (sBPaortic) measured arteriograph Task Force Monitor, respectively. Eighty-two suffered prolonged according criteria, while 19 did not. Patients had higher FIS scores (p = 0.02), lower central 0.02) 0.03). For a one-point increase component CFQ scale, risk increases by 34%. an sBPaortic 1 mmHg, decreases 5%. unit sympathovagal balance, 330%. Higher sympathetic activity rest are related increased PEM, reduced PEM. However, none between group significant after FDR correction, therefore conclusions should be treated caution replicated further studies.